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From Office 12 of the Istanbul Main Bus Terminal (Büyük Otogar), buses of the Çagdas company go from Istanbul to Nigde, on the southern verge of Cappadocia.
Others of the Nur company go to Adana, Antakya, Ceyhan and Iskenderun in the province of Hatay, and the company will sell you a through ticket to Halep (Halab, Aleppo) and Sam (Dimashk, Damascus) in Syria.
Alphabetical List of Destinations
Full List of Offices/Perons & Companies
Istanbul Bus Terminal (Otogar) Homepage